Immune cell modulation of oligodendrocyte lineage cells
نویسندگان
چکیده
منابع مشابه
Single-cell transcriptomic analysis of oligodendrocyte lineage cells
Oligodendrocytes (OLs) are glial cells in the central nervous system (CNS), which produce myelin, a lipid-rich membrane that insulates neuronal axons. The main function ascribed to OLs is to regulate the speed of electric pulse transmission, and as such OLs have been widely considered as a single and discrete population. Nevertheless, OLs and their precursor cells (OPCs) throughout the CNS have...
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Oligodendrocytes are the myelinating cells of the vertebrate central nervous system, responsible for generating the myelin sheath necessary for saltatory conduction. The use of increasingly sophisticated genetic tools, particularly in mice, has vastly increased our understanding of the molecular mechanisms that regulate development of the oligodendrocyte lineage. This increased reliance on the ...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2020
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2019.134601